Application of Monte Carlo simulation technology in OCT imaging contrast

HU Hai-feng; YAO Jian-quan; ZHANG Fan

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Application of Monte Carlo simulation technology in OCT imaging contrast

更新时间：2020-08-12

- Application of Monte Carlo simulation technology in OCT imaging contrast
- Optics and Precision Engineering Vol. 12, Issue 1, Pages: 94-99(2004)
- 作者机构：
  
  1. 天津大学, 精密仪器与光电子工程学院, 激光与光电子研究所, 教育部光电信息技术科学重点实验室, 天津, 300072
  2. 南开大学, 天津大学, 联合研究院, 天津, 300072
  3. 华中科技大学, 激光技术国家重点实验室, 湖北, 武汉430074
- 作者简介：
- 基金信息：
- DOI：
  CLC： O435
- Received：24 August 2003，
  
  Revised：10 November 2003，
  
  Published Online：15 February 2004，
  
  Published：15 February 2004
- 稿件说明：
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胡海峰, 姚建铨, 张帆. 利用Monte Carlo模拟技术研究OCT图像对比度[J]. 光学精密工程, 2004,(1): 94-99

HU Hai-feng, YAO Jian-quan, ZHANG Fan. Application of Monte Carlo simulation technology in OCT imaging contrast[J]. Editorial Office of Optics and Precision Engineering, 2004,(1): 94-99
胡海峰, 姚建铨, 张帆. 利用Monte Carlo模拟技术研究OCT图像对比度[J]. 光学精密工程, 2004,(1): 94-99 DOI：

HU Hai-feng, YAO Jian-quan, ZHANG Fan. Application of Monte Carlo simulation technology in OCT imaging contrast[J]. Editorial Office of Optics and Precision Engineering, 2004,(1): 94-99 DOI：

摘要

建立了光在生物组织中传播的模型

利用MonteCarlo模拟技术快速计算和可移植性的优点

研究了OCT图像对比度与显微物镜数值孔径、焦距深度、时间门参数的关系

并给出它们的关系曲线.通过在所建立的模型基础上加入透镜透过率函数和光学传递函数

弥补了以往程序只能模拟光在生物组织中传播行为的缺点.该模型不仅可以分析生物组织图像与生物光学特性的关系

而且还可以指导OCT结构的完善和创新.模拟结果表明:在构建OCT时

参考臂与样品臂的这两个显微物镜的数值孔径越大

生物组织的采样深度越浅

处理信号的时间门宽度越小(但时间门宽度不能小于激光脉冲时间)

混浊生物组织图像对比度越好.

Abstract

The relationship between OCT imaging contrast and objective numerical aperture(NA)

focus depth

time gate has been studied with interrelationship established using the model established for the propagation of light in bio-tissue and the Monte Carlo simulation technology. Other simulation programs can not be used to simulate any effect of optical components

such as microscope and time gate

on OCT images. The drawback of other simulation programs to simulate the light propagation in bio-tissue only has been overcome by adding some lens permeation ratio functions and optical transmission functions to the models established. This can be used to analyze the relationship between the bio-tissue images and the bio-optical properties

and to promote the perfection and innovation of OCT configuration. Simulation results show that

while OCT is constructed

the larger the objective NAs of reference arm and sample arm are

the shallower the sample depth of bio-tissue is

and the more narrow the time gate of processing signal is

but it can not be less than laser pulse time

the better the imaging contrast of turbid tissue is.

关键词

Keywords

references

HUANG D, SWANSON E A, LIN C P,et al. Optical coherence tomography[J].Science,1991,254:1178-1181.

PALIAFITO C A, HEE M R, LIN C P, et al.Imaging of macular disease with optical coherence tomography[J]. Ophthalmology,1995,120:1217-1229.

BREZINSKI M E, TEARNEY G J, BOUMA B E, et al.Optical coherence tomography for optical biopsy: Properties and demonstration of vascular pathology[J]. Circulation, 1996,93:1206-1213.

BREZINSKI M E, FUJIMOTO J G. Optical coherence tomography: high-resolution imaging in nontransparent tissue[J].Quantum Electronics, 1999,5(4):1185-1192.

YADLOSKY M J, SCHMITT J M, BONNER R F.Multiple scattering in optical coherence microscopy[J].Appl Opt,1995,34:5699-5707.

PAN Y T, BIRNGRUBER R, ROSPERICH O J,et al.Low-coherence optical tomography in turbid tissue: theoretical analysis[J]. Appl Opt,1995,34:6564-6574.

SCHMITT J M, KNUTTEL A. Model of optical coherence tomography of heterogeneous tissue[J].J Opt Soc Am,1997,A14:1231-1242.

王建设.空间光学遥感器轨道外热流的模拟[J].光学精密工程2000,8(4):328-331.WANG J SH. Simulation of orbit external thermal flux of a space optical remote sensor[J]. Optics and Precision Enginering,2000,8(4):198-203.(in Chinese)

YAO G, WANG L H.Propagation of polarized light in turbid media:simulated animation sequences[J]. Optics Express,2000,7(5):198-203.

PENG D Q,LI H,XIE SH S. Monte Carlo simulation in tissue optics[J].Journal of Optoelectronics,2003,14:106-110.

TUCHIN V V, UTZ S R, YAROSLAVSKY I V,et al.Tissue optics,light distribution,and spectroscopy[J].Opt Eng,l994,33(10):3l78-3188.

WANG L V, JACQES S L, ZHENG L Q.Monte Carlo modeling of photon transport in multi-layered tissue[J]. Computer Methods and Programs in Biomedicine,1995,47:131-146.

HEE M R, IZATT J A, JACOBSON J M,et al.Femtosecond transillumination optical coherence tomography[J].Opt Lett,1993,18:950-952.

SCHMIDT A, COREY R, SAULLNIER P.Imaging through random media by use of low-coherence optical heterodyning[J].Opt Lett,1995,20:404-406.

DUBOIS A,VABRE L. High-resolution full-field optical coherence tomography with a Linnik microscope[J]. Appl Opt,2002,41(4):805-812

SCHMITT J M. Optical coherence tomography(OCT):a review[J]. IEEE Journal of Selected Topic in Quantum Electronics,1999,5(4):1205-1215.

佟首峰,阮锦,郝志航.CCD图像传感器降噪技术的研究[J].光学精密工程,2000,8(2):140-146.TONG SH F, RUAN J, HAO ZH H.Noise reducing scheme on output signal of CCD[J].Optics and Precision Engineering,2000,8(2):140-146.(in Chinese)

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