Axial intensity in a fiber-optic confocal microscope

LIU Yong; CHEN Jia-bi; REN Qiu-shi; WANG Cheng; LI Wan-rong

doi:null

您当前的位置：

首页 >

文章列表页 >

Axial intensity in a fiber-optic confocal microscope

更新时间：2020-08-12

- Axial intensity in a fiber-optic confocal microscope
- Optics and Precision Engineering Vol. 13, Issue 5, Pages: 608-612(2005)
- 作者机构：
  
  1. Optical and Electronic Information Engineering College,University of Shanghai for Science &amp
  2. Institute for Laser Medicine &amp
  3. Technology Shanghai,China,200093
  4. Bio-photonics,Shanghai Jiaotong University Shanghai,China,200030
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Received：16 March 2005，
  
  Revised：27 June 2005，
  
  Published Online：30 October 2005，
  
  Published：30 October 2005
- 稿件说明：
移动端阅览
LIU Yong, CHEN Jia-bi, REN Qiu-shi, et al. Axial intensity in a fiber-optic confocal microscope[J]. Optics and precision engineering, 2005, 13(5): 608-612.
DOI：

LIU Yong, CHEN Jia-bi, REN Qiu-shi, et al. Axial intensity in a fiber-optic confocal microscope[J]. Optics and precision engineering, 2005, 13(5): 608-612. DOI：

摘要

A fiber-optic confocal microscope has been analyzed by Fourier optics.It is found that the detected light intensity has three parts

each of which is depennted on the coupled lens

the detective lens

and the part comprised of the fiber and the microprobe.The simulated results show that the less the value of the parameter

which is dependent on the fiber and microprobe

the higher the axial resolution of the system is. For the case

→∞

the axial resolution is zero

which is corresponding to the conventional microscope.as

≤1

the axial resolution changes slightly

and is close to the optimal value

which is corresponding to the perfect confocal microscope.when the reflective loss takes place at the end of fiber

the contrast of axial intensity will decrease.All that will help the design of endoscope with confocal microscope at cellular level.

Abstract

A fiber-optic confocal microscope has been analyzed by Fourier optics.It is found that the detected light intensity has three parts

each of which is depennted on the coupled lens

the detective lens

and the part comprised of the fiber and the microprobe.The simulated results show that the less the value of the parameter

which is dependent on the fiber and microprobe

the higher the axial resolution of the system is. For the case

→∞

the axial resolution is zero

which is corresponding to the conventional microscope.as

≤1

the axial resolution changes slightly

and is close to the optimal value

which is corresponding to the perfect confocal microscope.when the reflective loss takes place at the end of fiber

the contrast of axial intensity will decrease.All that will help the design of endoscope with confocal microscope at cellular level.

关键词

Keywords

references

. SABHARWAL Y S,ROUSE A R.Slit-scanning confocal microendoscope for high-resolution in vivo imaging[J].Appl.Opt.,1999,38:7133-7144.

. KNITTEL J.Endoscope-compatible confocal microscope using a gradient index-lens system[J].Opt.Commu,2001,188:267-273

. GMITRO A F.Confocal microscopy through a fiber-optic imaging bundle[J].Opt.lett.,1993,18:565-567

. SUNG K B.Near real time in vivo fiber optic confocal microscopy:sub-cellular structure resolved[J]. J.Micros,2002,207:137-145.

. WU CH Q.Optical waveguide theory[M].Tsinghua University press,:80-82.

. GU M,GAN X,SHEPPARD C J P.Three-dimensional coherent transfer functions in fiber-optical confocal scanning microscopes[J].J.Opt.Soc.A.,1991,7:1019-1025.

Views

271

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

AI问答

Address：No.3888 Dong Nanhu Road, Changchun, Jilin, China Postal code：130033
Tel：0431-86176855 Email：gxjmgc@ciomp.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 吉ICP备11002662号-17 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰