Development of an Optical Coherence Tomography Imaging System in Ophthalmology

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Development of an Optical Coherence Tomography Imaging System in Ophthalmology

Article | 更新时间：2020-08-12

- Development of an Optical Coherence Tomography Imaging System in Ophthalmology
- Optics and Precision Engineering Vol. 16, Issue 3, Pages: 438-443(2008)
- 作者机构：
  
  清华大学深圳研究生院光学检测与成像实验室
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Received：21 December 2007，
  
  Revised：21 January 2008，
  
  Published Online：22 March 2008，
  
  Published：22 March 2008
- 稿件说明：
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何卫红. 眼底OCT成像系统的研制[J]. 光学精密工程, 2008,16(3):438-443

Development of an Optical Coherence Tomography Imaging System in Ophthalmology[J]. Optics and precision engineering, 2008, 16(3): 438-443.
何卫红. 眼底OCT成像系统的研制[J]. 光学精密工程, 2008,16(3):438-443 DOI：

Development of an Optical Coherence Tomography Imaging System in Ophthalmology[J]. Optics and precision engineering, 2008, 16(3): 438-443. DOI：

摘要

光学相干层析（OCT）成像技术是一种高分辨率生物成像手段，能非侵入、无接触地对活体内部的结构与生理功能进行检测。在生物医学领域，OCT主要还是应用在眼科学，主要是因为近红外光很容易穿透人体眼睛介质。本文利用中心波长为854nm的宽带弱相干光源SLD实现了光学相干层析成像系统在眼科中的应用。系统采用傅里叶域光学快扫描延迟线实现了快速扫描成像，成像深度为3mm。我们自行设计了一种用于眼底信号探测的眼科探头

包括：眼底OCT成像光路；眼底照明光路；眼底照相光路，获得了眼底黄斑和眼底视神经乳头的眼底照片以及OCT图像。

Abstract

Optical coherence tomography (OCT) is a high resolution biomedical imaging method

allowing for non-invasive and contace-free detecting of internal tissue structure and physiology. Ophthalmology is still the dominating field of biomedical OCT. The most important reason for that is the high transmittance of ocular media. An OCT system with broadband source (SLD) centered at 854 nm wavelength is applied for imaging in ophthalmology. Based on Fourier-domain rapid scanning optical delay line

the system is capable of imaging depth of 3mm. A device detecting the signal of eyeground is provided in this article. This device constitutes of the optical path for OCT imaging in the eyeground

the optical path for lighting of the eyeground

the optical path for obtainning photograph of the eyeground. The OCT images of macular region and optic nerve in the eyeground have been obtained.

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Related Author

WANG Zhi-bin

SHI Guo-hua

HE Yi

DING Zhi-hua

ZHANG Yu-dong

ZHANG Qin-qin

WU Xiao-jing

ZHU Si-wei

Related Institution

Institute of Optics & Electronics, Chinese Academy of Sciences

Graduate University of Chinese Academy of Sciences

State Key Laboratory of Modern Optical Instrumentation, Zhejiang University

Key Laboratory of Optical Information Science & Technology of the Ministry of Education,Institute of Modern Optics, Nankai University

Laboratory of Molecular Medicine and Nano Optics, Nankai University Affiliated Hospital

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