The application of Spectral domain optical coherence tomography in oral cavity tissue

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The application of Spectral domain optical coherence tomography in oral cavity tissue

Information sciences | 更新时间：2020-08-12

- The application of Spectral domain optical coherence tomography in oral cavity tissue
- Optics and Precision Engineering Vol. 19, Issue 8, (2011)
- 作者机构：
  
  南开大学2. 天津医科大学第二医院3. 南开大学人民医院4. Clemson大学5. 天津市南开大学现代光学研究所
- 作者简介：
- 基金信息：
- DOI：
  CLC： R781.7;R814.42
- Received：03 March 2011，
  
  Revised：11 April 2011，
  
  Published Online：21 October 2011，
  
  Published：25 August 2011
- 稿件说明：
移动端阅览
张芹芹,彭诚,吴晓静,朱思伟,高志,袁小聪. 谱域光学相干层析成像系统在口腔疾病诊断中的应用[J]. 光学精密工程, 2011, 19(8): 0-0.

ZHANG Qin-Qin,PENG Cheng,WU Xiao-Jing,ZHU Sai-Wei,GAO Zhi,YUAN Xiao-Cong. The application of Spectral domain optical coherence tomography in oral cavity tissue[J]. Editorial Office of Optics and Precision Engineering, 2011, 19(8): 0-0.
张芹芹,彭诚,吴晓静,朱思伟,高志,袁小聪. 谱域光学相干层析成像系统在口腔疾病诊断中的应用[J]. 光学精密工程, 2011, 19(8): 0-0. DOI：

ZHANG Qin-Qin,PENG Cheng,WU Xiao-Jing,ZHU Sai-Wei,GAO Zhi,YUAN Xiao-Cong. The application of Spectral domain optical coherence tomography in oral cavity tissue[J]. Editorial Office of Optics and Precision Engineering, 2011, 19(8): 0-0. DOI：

摘要

目的：口腔颌面部器官暴露或多有通道与外界相通，成为OCT系统实验研究的优选对象。方法：谱域光学相干层析术（Optical Coherence Tomography，简称OCT）系统是在时域OCT系统上发展而来的，具有非入侵，非接触，具有高分辨率等特点的成像技术，同时由于无需纵向扫描，实现了快速扫描成像，使实时、在体成像成为可能，在医学领域得到了广泛应用。自行设计并搭建了一套便于集成化的光纤式谱域OCT系统，纵向分辨率为7.3μm，横向分辨率达到9.5μm，在空气中的成像深度为3.14mm；在此基础上，针对口腔内唾液腺导管内壁的组织形态进行了研究。结果：得到的OCT图像与相对应的病理切片图片进行比较，获得了腮腺导管内壁组织的层析结构。结论：腮腺导管内壁组织的层析结构的获得，这对临床医学上的口腔唾液腺疾病的无创检查和早期诊断具有一定的指导意义。

Abstract

Objective: Because of the organ exposure in oral cavity

the oral cavity tissues become the optimal object of OCT. Method: Spectral domain optical coherence tomography (SDOCT) is a non-invasive

contact-free and high resolution technology developed by time domain OCT. Spectral domain OCT (SD-OCT) improves the imaging speed

as it can obtain the information of the whole depth without the mechanical scanning which is possible to obtain the real-time and vivo images. By self-designing

the SDOCT set of fiber type has been constructed which is easy to integration; the longitudinal resolution is 7.3μm; lateral resolution is 9.5μm; and the imaging depth can be achieved 3.14 mm in air. The histomorphological features of the salivary glands have been studied based on the set. Result: The OCT images are compared with the pathological sections. The microstructures of the parotid gland have been obtained by the comparisons. Conclusion: The results have indicative effects to the early diagnosis of the oral cavity tissue and the non-harmful examination.

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Related Author

PENG Cheng

ZHANG Qin-qin

WU Xiao-jing

ZHU Si-wei

GAO Zhi

YUAN Xiao-cong

Related Institution

天津医科大学第二医院口腔科

南开大学现代光学研究所光电信息技术科学教育部重点实验室

南开大学人民医院分子医学与纳米光学实验室

Department of Bioengineering, Clemson University, Clemson, South Carolina

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