Optical Measuring Method and Apparatus Study On Hemoglobin Concentration in Whole Blood

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Optical Measuring Method and Apparatus Study On Hemoglobin Concentration in Whole Blood

Article | 更新时间：2020-08-13

- Optical Measuring Method and Apparatus Study On Hemoglobin Concentration in Whole Blood
- Optics and Precision Engineering Vol. 17, Issue 12, Pages: 2893-2898(2009)
- 作者机构：
  
  哈尔滨工业大学（威海）2. 哈尔滨工业大学
- 作者简介：
- 基金信息：
- DOI：
  CLC： TG156
- Received：19 January 2009，
  
  Revised：24 February 2009，
  
  Published Online：25 December 2009，
  
  Published：25 December 2009
- 稿件说明：
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黄博,姚玉峰,姜瑞举,郑亚军. 血红蛋白浓度的光学测量方法与装置研究[J]. 光学精密工程, 2009,17(12):2893-2898

Optical Measuring Method and Apparatus Study On Hemoglobin Concentration in Whole Blood[J]. Optics and precision engineering, 2009, 17(12): 2893-2898.
黄博,姚玉峰,姜瑞举,郑亚军. 血红蛋白浓度的光学测量方法与装置研究[J]. 光学精密工程, 2009,17(12):2893-2898 DOI：

Optical Measuring Method and Apparatus Study On Hemoglobin Concentration in Whole Blood[J]. Optics and precision engineering, 2009, 17(12): 2893-2898. DOI：

摘要

血红蛋白测定是临床测定最广的项目之一，很有必要研制一种无毒害的便携精确测定装置用于移动采血和健康监护等环境。本文基于叠氮高铁血红蛋白溶液的吸收光谱曲线设计了二次吸收测量机理，并明确了浓度计算公式；基于该测量方法研制了便携式血红蛋白浓度定量测定装置，并阐述了装置中药剂容腔微片、测量装置与控制系统的详细方案；该装置采用一次性的配药微片可在30-60秒内实现未稀释未溶血全血的在线快速测量。临床试验表明，对比氰化高铁血红蛋白法相关性可达0.9836，准确性达到96.32%。利用该测定仪的便携性、在线快速检测特性，可广泛应用于移动采供血机构、运动员机能评定以及家庭保健等。

Abstract

Hemoglobin concentration measurement is one of the most widely used Clinic analysis project

It is necessary to research a hemoglobin measurement apparatus applied to blood collection and healthy care domain with the advantage of no contaminate

portable and accurate. Secondary absorb measurement mechanism is designed based on the absorb spectrum chart of Azide methemoglobin

and the concentration equation is derived

an instrument based on above method which could detect hemoglobin within 30 to 60 seconds was developed. Testing principle

measuring mechanism

control system and parameters calibration are all introduced in the paper in detail. As the clinical trials show: compared with cyaniding methemoglobin (Fe3+)

the pertinence of the result of the measurement can be 0.9836

the veracity can be 96.32%. Because of the portability and the characteristic of quick-testing online

the instrument can be widely used in moving blood collecting stations

judging the function of the athletes and family health care

and it is important to them.

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Related Institution

College of Mechanical Engineering， Anhui University of Technology

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School of Instrument Science and Optoelectronic Engineering, Hefei University of Technology

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