Dynamic effect in process of stopping capillary by step valve in microchannel

ZHANG Ping; XU Lei; DENG Yong-bo

doi:10.3788/OPE.20111912.2919

您当前的位置：

首页 >

文章列表页 >

Dynamic effect in process of stopping capillary by step valve in microchannel

Article | 更新时间：2020-08-12

- Dynamic effect in process of stopping capillary by step valve in microchannel
- Optics and Precision Engineering Vol. 19, Issue 12, Pages: 2919-2926(2011)
- 作者机构：
  
  1. 中国科学院长春光学精密机械与物理研究所应用光学国家重点实验室,吉林长春 130033
  2. 中国科学院研究生院北京,100039
  3. 中国科学院苏州生物医学工程技术研究所,江苏苏州 215163
- 作者简介：
- 基金信息：
- DOI：10.3788/OPE.20111912.2919
  CLC： TH134.1;TH703
- Received：14 April 2011，
  
  Revised：18 May 2011，
  
  Published Online：25 December 2011，
  
  Published：25 December 2011
- 稿件说明：
移动端阅览
张平, 徐磊, 邓永波. 微通道内台阶阀截止过程中的毛细流动动态效应[J]. 光学精密工程, 2011,19(12): 2919-2926

ZHANG Ping, XU Lei, DENG Yong-bo. Dynamic effect in process of stopping capillary by step valve in microchannel[J]. Editorial Office of Optics and Precision Engineering, 2011,19(12): 2919-2926
张平, 徐磊, 邓永波. 微通道内台阶阀截止过程中的毛细流动动态效应[J]. 光学精密工程, 2011,19(12): 2919-2926 DOI： 10.3788/OPE.20111912.2919.

ZHANG Ping, XU Lei, DENG Yong-bo. Dynamic effect in process of stopping capillary by step valve in microchannel[J]. Editorial Office of Optics and Precision Engineering, 2011,19(12): 2919-2926 DOI： 10.3788/OPE.20111912.2919.

摘要

分析了由亲/疏水性不同壁面组成的微通道内毛细流动的动态效应对台阶阀截止功能的影响和在台阶阀截止过程中毛细流动动态效应与台阶阀前微通道长度的关系。根据毛细被动阀的工作原理和能量守恒原理

得出台阶阀有效截止时

台阶阀前微通道临界长度的计算公式。通过数值仿真得到临界长度所对应的计算长度

当台阶阀前微通道实际长度大于等于计算长度时

台阶阀即可有效截止。用聚二甲基硅氧烷(PDMS) 和玻璃为材料键合制作微流控芯片

在三面疏水、一面亲水的矩形微通道内进行了台阶阀截止实验。对于深度为40 m

宽度为200~400 m的系列微通道

台阶阀前微通道的计算长度为4.531 6~10.081 m

在台阶阀前微通道实际长度为10~2 000 m的微流控芯片内进行的台阶阀截止实验表明

即使台阶阀前微通道实际长度为10 m

台阶阀也能有效截止毛细流动。因此

在微通道内台阶阀截止过程中毛细流动的动态效应可以忽略。

Abstract

The relationship between the dynamic effect of a capillary and the length of microchannel in front of a step valve was researched

then the influence of dynamic effect in the process of stopping the capillary in microchannel formed by hydrophobic and hydrophilic walls on the step valve was analyzed. According to the working principle of the passive valve of capillary and energy conservation law

the critical length in front of the step valve was calculated when the step valve stoped the capillary. The calculated length corresponding to the critical length was obtained by numerical simulation. It shows that when the actual length in front of the step valve is greater than or equal to the calculated length

the valve can stop the capillary effectively. The step valves were fabricated by bonding polydimethylsiloxane (PDMS) to glass. Experiments of stopping the capillary by the step valve were performed in a rectangular microchannel formed by three hydrophobic PDMS walls and one hydrophilic glass wall. For the series of microchannel with a depth of 40 m and widths from 200 m to 400 m

the calculated length in front of the step valve is from 4.531 6 m to 10.081 m. In the experiments

the actual length before the step valves for effectively stopping the capillary is in the interval from 10 m to 2 000 m. The results show that even if the actual length in front of the step valve is 10 m

the step valve can also stop the capillary. Therefore

the dynamic effect of the capillary can be ignored in stopping the step valves in the microchannel.

关键词

Keywords

references

STEMME E, STEMME G. A valveless diffuser/nozzlebased fluid pump [J].Sensors and Actuators,1993,A39:159-167.[2] MORRIS C J, FORSTER F K. Low-order modeling of resonance for fixed-valve micropumps based on first principles pump [J]. Microelectromechanical Systems,2003,12:325-334.[3] KWANG W O,CHONG H A. A review of microvalves[J]. Jounal of Micromechanics and Microengineering,2006,16:13-39.[4] 张平,胡亮红,刘永顺. 主辅通道型微混合器的设计与制作 [J]. 光学精密工程,2010,18(4):872-879. ZHANG P,HU L H,LIY Y S.Design and fabrication of microm ixer with main-assist channels [J].Opt. Precision Eng.,2010,18(4):872-879.(in Chinese)[5] ALAIN G, CYRIL D. Modeling and fabrication of capillary stop valves for planar microfluidic systems[J].Sensors and Actuators, 2006,130-131:601-608.[6] ANDERSSON H, WIJNGAART W, GRISS P. Hydrophobic valves of plasma deposited octafluorocyclobutane in DRIE channels[J]. Sens. Actuat,2001,B75:136-141.[7] YAN Y F, ZHAO Y Z, XIONG Y Y, et al.Passive valves based on hydrophobic microfluidics[J].Sensors and Actuators, 2003,A208:138-143.[8] MARC M, JIM Z, GUANG Y J, et al.Lab on a CD. Annu. Rev. Biomed. Eng, 2006.[9] WEI F H, QIU S L, YONG L. Capillary filling flows inside patterned-surface microchannels[J]. Chemical Engineering & Technology,2006,29(6):716-723.[10] JERRY M C,HUANG P C, MOU G L. Analysis and experiment of capillary valves for microfluidics on a rotating disk [J].Microfluid Nanofluid,2008,4:427-437.[11] HAN S C, H Y K, JI Y K, et al. How the capillary burst microvalve works [J].Journal of Colloid and Interface Science, 2007,306:379-385.[12] RICHARD M M, ROBERT A, STERLING E M. A passive fluid valve element for a high-density chemical synthesis machine.MSM 99,1999:526-529.[13] MAN P F,MASTRANGELO C H, BURNS M A, et al.. Microfabricated capillary driven c valves and simple injector. MEMS Conference, Heidelberg, Germany, January 25-29, 1998.[14] MELIN J, ROXHED N, GIMENEZ G, et al. A liquid-trigged liquid microvalve for on-chip flow control [J].Sensors and Actuators,2004,B100:463-468.[15] LUCAS R. Ueber das zeitgesetz des kapillaren zufstiegs von fl ssigkeiten [J].Colloid & Polymer Sciense,1918,23(5):15-22.[16] WASHBURN E W. The dynamics of capillary flow [J].Physical Review, 1921, 2:273-283.[17] ZHMUD B V, TIBERG F, HALLSTENSSON K. Dynamics of capillary rise [J]. Journal of Colloid and Interface Science,2000,228:263-269.[18] ENOCH K, GEORGE M W. Imbibition and flow of wetting liquids in noncircular capillaries [J]. J. Phys. Chem,1997,B:855-863.[19] 邓永波,张平,杜新,等. 亲/疏水性不同壁面组成微通道深宽比与通道内自发毛细流 [J]. 光学精密工程,2010,18(7):1562-1567. DENG Y B,ZHANG P,DU X, et al. Aspect ratio for micro-channels with nonuniform surface properties and spontaneous capillary [J]. Opt. Precision Eng.,2010,18(7):1562-1567.(in Chinese)[20] EMMANUEL D, ANDRE B, HEINZ S, et al. Microfluidic networks for chemical patterning of substrates: design and application to bioassays [J]. Am. Chem. Soc.,1998,120(3):500-508.[21] VILLE J, SAMI F. Capillarity in microfluidic channels with hydrophilic and hydrophobic walls [J].Microfluidics Nanofluidics, 2008,5(4):443-448.[22] YULII D S. Capillary flows with forming interfaces [M]. Chapman & Hall/CRC,2007.[23] KUNG C F, CHIU C F, CHEN C F, et al. Blood flow driven by surface tension in a microchannel[J].Microfluidics Nanofluidics,2008,6(5):693-697.[24] 金庆辉,庄贵生,刘菁,等. 微流控分析芯片在线尿中蛋白及LDH同工酶检测 [J]. 光学精密工程,2005,13(2):151-157. JIN Q H,ZHUANG G S,LIU Q, et al. On-line detection of urinary protein and lactate dehydrogenase isoenzyme by capillary electrophoresis microchiop [J]. Opt. Precision Eng., 2005,13(2):151-157.(in Chinese)

Views

463

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Study on analysis of dynamic effect in process of stopping capillary by step valve in microchannel

Aspect ratio for microchannels with nonuniform surface properties and spontaneous capillary

Related Author

徐磊

张平

邓永波

DENG Yong-bo

ZHANG Ping

DU Xin

WU Yi-hui

LIU Zhen-yu

Related Institution

中科院长春光学精密机械与物理研究所应光室微机械组2. 中国科学院长春光学精密机械与物理研究所3. 长春光机所

State Key Laboratory of Applied Optics,Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033,China

Graduate University of Chinese Academy of Sciences, Beijing 100039, China

Suzhou Institute of Biomedical Engineering and Technology,Chinese Academy of Sciences,Suzhou 215163,China

AI问答

Address：No.3888 Dong Nanhu Road, Changchun, Jilin, China Postal code：130033
Tel：0431-86176855 Email：gxjmgc@ciomp.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 吉ICP备11002662号-17 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰