Integrated microfluidic nitrite fluorescence optical fiber sensor based on optical fiber with microholes on surface

ZHAO En-ming; LI En-tao; TENG Ping-ping; LIU Chun-lan; GUO Xiao-hui; LI Song; YANG Xing-hua

doi:10.3788/OPE.20152308.2158

您当前的位置：

首页 >

文章列表页 >

Integrated microfluidic nitrite fluorescence optical fiber sensor based on optical fiber with microholes on surface

更新时间：2020-08-12

- Integrated microfluidic nitrite fluorescence optical fiber sensor based on optical fiber with microholes on surface
- Optics and Precision Engineering Vol. 23, Issue 8, Pages: 2158-2163(2015)
- 作者机构：
  
  1. 哈尔滨工程大学理学院, 黑龙江哈尔滨 150001
  2. <br /> 2. 哈尔滨第一机械集团设计研究所,黑龙江哈尔滨,150056
- 作者简介：
- 基金信息：
- DOI：10.3788/OPE.20152308.2158
  CLC： TN253
- Received：20 March 2015，
  
  Revised：11 May 2015，
  
  Published：25 August 2015
- 稿件说明：
移动端阅览
赵恩铭, 李恩涛, 滕平平等. 基于表面开孔光纤的集成式亚硝酸盐微流荧光传感器[J]. 光学精密工程, 2015,23(8): 2158-2163

ZHAO En-ming, LI En-tao, TENG Ping-ping etc. Integrated microfluidic nitrite fluorescence optical fiber sensor based on optical fiber with microholes on surface[J]. Editorial Office of Optics and Precision Engineering, 2015,23(8): 2158-2163
赵恩铭, 李恩涛, 滕平平等. 基于表面开孔光纤的集成式亚硝酸盐微流荧光传感器[J]. 光学精密工程, 2015,23(8): 2158-2163 DOI： 10.3788/OPE.20152308.2158.

ZHAO En-ming, LI En-tao, TENG Ping-ping etc. Integrated microfluidic nitrite fluorescence optical fiber sensor based on optical fiber with microholes on surface[J]. Editorial Office of Optics and Precision Engineering, 2015,23(8): 2158-2163 DOI： 10.3788/OPE.20152308.2158.

摘要

利用中空悬挂芯光纤研制了一种将荧光猝灭反应区建立在空心光纤内部的光纤集成荧光在线微流传感器。利用CO

激光器在光纤表面刻蚀微孔

使得试剂可由微孔注入光纤内部并混合形成稳定的微流。在悬挂芯光纤纤芯倏逝场的激发下

指示剂分子产生荧光

所产生的荧光被耦合到纤芯内部并在出射端被检测。文中利用光纤内部的荧光猝灭反应实验确定了亚硝酸盐溶液的浓度。结果显示:微流可在短时间通过光纤

传感器能以较快的速度检测溶液浓度。另外

当亚硝酸盐溶液的浓度为0.1~2.6 mmol/L时

荧光猝灭程度与溶液浓度呈较好的线性关系

结果证明了该集成式光纤内微流控传感器方案用于微量荧光检测的可行性。

Abstract

An in-fiber integrated fluorescence online optofluidic sensor was developed by using a hollow optical fiber with a suspended core

in which the micro-region of the sensor for fluorescence quenching reaction was built in the hollow optical fiber. Microholes on the surface of the fiber were etched by a CO

laser

the fluorescence reagents could be injected into the optical fiber via the microholes and was mixed to form stable microflows in the fiber. Concurrently

indicator molecules were excitated by the evanescent field of the suspended core

the fluorescence was well coupled into the core and was detected in the exited end. The concentration of nitrite was determined by fluorescence quenching reaction during optofluidic reaction in the optical fiber. Experimental results indicate that the microflows could flow through the optical fiber in a short time

therefore

the sensor detects the solution concentration in a fast response rate.Moreover

the fluorescence response of the sensor is nearly linear depending on the concentration of nitrate in the range of 0.1-2.6 mmol/L

which reveals the feasibility of the integrated in-fiber optofluidic method for trace fluorescence detection.

关键词

Keywords

references

LIU S, ZHAO Y, PARK J W, et al.. Correlated electrical and optical analysis of single nanoparticles and biomolecules on a nanoporegated optofluidic chip [J]. Nano Lett., 2014, 14(8): 4816-4820.

[2] PERSICHETTI G, TESTA G, BERNINI R. Optofluidic jet waveguide enhanced Raman spectroscopy [J]. Sens. Actuators B, 2015, 207: 732-739.

[3] BERTUCCI A, MANICARDI A, CANDIANI A, et al.. Detection of unamplified genomic DNA by a PNA-based microstructured optical fiber (MOF) Bragg-grating optofluidic system [J]. Biosens. Bioelectron., 2015, 63: 248-254.

[4] RODRGUEZ-RUIZ I, LLOBERA A, VILA-PLANAS J, et al.. Analysis of the structural integrity of SU-8-based optofluidic systems for small-molecule crystallization studies [J]. Anal. Chem., 2013, 85 (20): 9678-9675.

[5] QIAN W, ZHAO C, WANG Y, et al.. Partially liquid-filled hollow-core photonic crystal fiber polarizer [J]. Opt. Lett., 2011, 36 (16): 3296-3298.

[6] WANG Y, WANG D, LIAO C, et a0l.. Temperature-insensitive refractive index sensing by use of micro Fabry-Prot cavity based on simplified hollow-core photonic crystal fiber [J]. Opt. Lett., 2013, 38 (3): 269-271.

[7] 赵明富, 王念, 罗彬彬, 等, 可同时测量蔗糖浓度和温度的组合光纤光栅传感器[J]. 中国光学, 2014, 7(3):476-482. ZHAO M F, WANG N, LUO B B, et al.. Simultaneous measurement of temperature and concentration of sugar solution based on hybrid fiber grating sensor[J]. Chinese Optics, 2014,7(3):476-482.(in Chinese)

[8] ENGLICH F V, GRABKA M, LANCASTER D G, et al.. Magnetic field interaction with guided light for detection of an active gaseous medium within an optical fiber [J]. Opt. Express, 2013, 21(2): 2491-2499.

[9] 赵恩铭, 郑瑶, 刘岩鑫, 等. 基于内壁芯光纤的调制器件 [J]. 光学精密工程, 2013, 21(4):884-888. ZHAO E M, ZHENG Y, LIU Y X, et al.. Modulator device based on optical fiber with core on inner wall [J]. Opt. Precision Eng., 2013, 21(4):884-888.(in Chinese)

[10] 肖海斌,赵进辉,袁海超,等. 同步荧光光谱结合CARS变量优选预测猪肉中四环素残留含量 [J]. 光学精密工程,2013, 21(10): 2513-2519. XIAO H B, ZHAO J H, YUAN H CH, et al.. Determination of tetracycline content in pork by synchronous fluorescence spectroscopy with CARS method [J]. Opt. Precision Eng., 2013, 21(10): 2513-2519.(in Chinese)

[11] XU S, XU S H, ZHU Y S, et al.. A novel upconversion, fluorescence resonance energy transfer biosensor (FRET) for sensitive detection of lead ions in human serum [J]. Nanoscale, 2014, 6:12573-21579.

[12] 赵进辉,袁海超,洪茜,等. 基于纳米银粒子增强荧光测定鸭肉中土霉素残留量[J]. 光学精密工程,2014, 22(11): 2902-2907. ZHAO J H, YUAN H CH, HONG X, et al.. Determination of oxytetracycline content in duck meat using silver nanoparticle enhanced fluorescence [J].Opt. Precision Eng., 2014, 22(11): 2902-2907.(in Chinese)

[13] HAN J, XU M, WANG B, et al.. Low dose detection of radiation via solvent assisted fluorescence quenching [J]. J. Am. Chem. Soc., 2014, 136(13): 5090-5096.

[14] SHI X, GU W, PENG W, et al.. Sensitive Pb2+ probe based on the fluorescence quenching by graphene oxide and enhancement of the leaching of gold nanoparticles [J]. ACS Appl. Mater. Interfaces, 2014, 6(4): 2568-2575.

[15] WANG Q, WANG W, LEI J P, et al.. Fluorescence quenching of carbon nitride nanosheet through its interaction with DNA for versatile fluorescence sensing [J]. Anal. Chem., 2013,85(24): 12182-12188.

[16] NAWROCKI J, ANDRZEJEWSKI P. Nitrosamines and water [J]. J. Hazard. Mater., 2011, 189 (1-2): 1-18.

[17] JIANG Z, SUN S, KANG C, et al.. A new and sensitive resonance-scattering method for determination of trace nitrite in water with rhodamine 6G [J]. Anal Bioanal. Chem., 2005, 381: 896-900.

Views

283

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Temperature insensitive optical fiber dual-cavity salinity sensor

Fiber-optic temperature sensor based on enhanced Vernier effect

Optical fiber hydrogen sensor based on self-assembled of Au@Pd NPs monolayer film

External oil cavity coupled with EFPI partial discharge ultrasonic detection sensor

Escherichia coli fiber sensor based on modified graphene coated fiber Mach-Zehnder interference

Related Author

GAO Jiale

WANG Ji

MU Xiaoguang

YANG Yuqiang

LI Yitong

YANG Yuqiang

GAO Jiale

MU Xiaoguang

Related Institution

Research Center of Guangdong Smart Oceans Sensor Networks and Equipment Engineering， Guangdong Ocean University

College of Mechanical Engineering， Guangdong Ocean University

Guangdong Provincial Key Laboratory of Intelligent Equipment for South China Sea Marine Ranching， Guangdong Ocean University

Shenzhen Institute of Guangdong Ocean University

Shenzhen Institute， Guangdong Ocean University

AI问答

Address：No.3888 Dong Nanhu Road, Changchun, Jilin, China Postal code：130033
Tel：0431-86176855 Email：gxjmgc@ciomp.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 吉ICP备11002662号-17 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰