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1. 中国科学院 长春光学精密机械与物理研究所 应用光学国家重点实验室,吉林 长春,130033
2. 吉林大学 第一医院,吉林 长春,130000
收稿日期:2005-07-22,
修回日期:2006-06-18,
纸质出版日期:2006
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卢启鹏, 侯宝忠, 朱琳琳. 半导体激光血管内照射治疗静脉曲张的机理研究[J]. 光学精密工程, 2006,14(4): 589-593
LU Qi-peng, HOU Bao-zhong, ZHU Linlin. Mechanism of varicosity treated by semiconductor laser intravenous irradiation[J]. Editorial Office of Optics and Precision Engineering, 2006,14(4): 589-593
对利用半导体激光器治疗静脉曲张的可行性及治疗机理进行了研究。通过半导体激光对犬副头静脉进行血管内照射的临床试验
分析激光与血管组织及血液的相互作用
同时对激光血管内照射治疗静脉曲张的机理进行了研究。研究结果表明:半导体激光进行腔内静脉照射
由于血红蛋白对光的吸收
可以引起静脉腔内血栓形成、血管壁损伤、血管闭合
实现对静脉曲张的治疗;激光照射导致静脉腔内血栓形成
与血栓性静脉炎的形成机制不同
并没有影响全身凝血功能。
The mechanism and the feasibility of the treatment of varicose veins by semiconductor laser intravenous irradiation were analyzed. By laser irradiation for the cephalic veins of the dogs
the interaction between vascular tissue
blood and the laser beam was analyzed. Research results indicate that varicosity can be treated by means of endovenous thrombus formation
blood vessel wall damnification and vessel enclosure induced by light absorption of haemoglobin irradiated by semiconductor laser. The mechanism of endovenous thrombus formation induced by laser irradiation is different from thromboplastic phlebitis
thus endovenous thrombus formation doesnt affect whole body cruor function.
于柏生,张世国. 大隐静脉曲张治疗的现状[J]. 空军总医院学报,2002,189(4):243-244. YU B S ,ZHANG,S G. Treatment actuality of great saphenous vein [J].Journal of General Hospital of Air Force, PLA, 2002,189(4):243-244.(in Chinese)[2] WEISS R. Commentry on endovenous laser[J]. Dermatol Surg.2001,27(3):326-327[3] ZHANG L M,YANG G L,LI D J. High energy long duration frequency-doubled Nd:YAG laser and application to veins occlusion[J].SPIE ,5627:369-379.[4] 李忠明、骆清明. 激光对生物组织热和热致机械损伤的物理分析[J]. 激光生物学报,2000,9(2):81-84. LI Z M, LUO Q M. Physieal analysis on tissuesheat and heat-induced injury for laser irradiation[J].Acta Laser Biology Sinica, 2000,9(2) :81-84.[5] 黄英,李维敏,陆信武,等. DIOMED激光治疗下肢静脉曲张的初步报告[J]. 外科理论与实践,2003,8(3):237-239. HUANG Y, LI W M,LU X W,et al. A preliminary report on IOMED laser treatment of superficial varicosities of the lower limb[J]. Journal of Surgery: Concepts & Practice, 2003,8(3):237-239.[6] 朱琳琳,张来明. 半导体激光在血管病变治疗方面的应用[J]. 激光与红外,2005(5):328-330. ZHU L L,ZHANG L M.Reseach of treatment with semi conductor laser of vascular diseases[J].Laser & Infrared, 2005(5):328-330.(in Chinese)
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