Abstract: Objective: With the develop of the modern industry

magnetic field has become far more extensive effect to human body. Many magnetic healing instruments for different disease have come out

and some do have curative effect

but the mechanism of magnetic healing is not classified. This context has studied the effect of pulsating magnetic fields to rat cortical neurons. Transient outward K+ channel can maintain the rest potential and control the excitement of excitable cells .Method: This experiment use pulsating magnetic fields that frequency is 15Hz and the intensity is 1.4mT impose on the acutely isolated rat cortical neurons

and properties of transient outward K+ channel were studied using the whole-cell patch clamp technique. Result: The experiment revealed pulsating magnetic fields reduce the amplitudes of IA . Pulsating magnetic fields significantly affected the activation process of IA. The half-activation voltage and the slope factor of the activation curves changed by the pulsating magnetic fields’ exposure. The former altered from(13.25±2.22)mV to (30.98±4.11)mV（n＝6

P<0.05）and the latter from (24.00±2.05)mV和(23.30±2.13)mV（n=6

P<0.05）. Conclusion: The results show that pulsating magnetic fields can change the properties of transient outward K+ channel. Thus

the form and firing frequency of action potential is affected. Further

physiological functions of neurons are adjusted as a result of pulsating magnetic fields

which might contribute to the restoration and regeneration of damaged neurons.