Objective: Because of the organ exposure in oral cavity

the oral cavity tissues become the optimal object of OCT. Method: Spectral domain optical coherence tomography (SDOCT) is a non-invasive

contact-free and high resolution technology developed by time domain OCT. Spectral domain OCT (SD-OCT) improves the imaging speed

as it can obtain the information of the whole depth without the mechanical scanning which is possible to obtain the real-time and vivo images. By self-designing

the SDOCT set of fiber type has been constructed which is easy to integration; the longitudinal resolution is 7.3μm; lateral resolution is 9.5μm; and the imaging depth can be achieved 3.14 mm in air. The histomorphological features of the salivary glands have been studied based on the set. Result: The OCT images are compared with the pathological sections. The microstructures of the parotid gland have been obtained by the comparisons. Conclusion: The results have indicative effects to the early diagnosis of the oral cavity tissue and the non-harmful examination.