葡萄糖溶液光声信号时域与频域特性对比

王倩; 吕鹏飞; 何巧芝; 吕娜; 赵辉

doi:10.37188/OPE.20202811.2421

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葡萄糖溶液光声信号时域与频域特性对比

现代应用光学 | 更新时间：2020-12-09

- 葡萄糖溶液光声信号时域与频域特性对比
- Characteristics comparison of photoacoustic signal of glucose solution in time domain and frequency domain
- 光学精密工程 2020年28卷第11期页码：2421-2428
- 作者机构：
  
  上海交通大学仪器科学与工程系, 上海 200240
- 作者简介：
  
  [ "王倩(1995-)，女，湖北襄阳人，硕士研究生，2018年于华中科技大学获得学士学位，主要从事光声法无创血糖监测的研究。E-mail：qianwangVera@sjtu.edu.cn" ]
  赵辉(1965-)，男，辽宁阜新人，博士，教授，博士生导师，1986年、1989年、1994年于哈尔滨工业大学分别获得学士、硕士、博士学位，主要从事现代传感器、机器视觉、光电检测技术等方面的研究。E-mail：huizhao@sjtu.edu.cn ZHAO Hui, E-mail: huizhao@sjtu.edu.cn
- 基金信息：
  
  国家自然科学基金资助项目(61873168)
- DOI：10.37188/OPE.20202811.2421
  中图分类号： TH773;R318.6
- 收稿日期：2020-05-25，
  
  修回日期：2020-06-15，
  
  录用日期：2020-6-15，
  
  纸质出版日期：2020-11-25
- 稿件说明：
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王倩, 吕鹏飞, 何巧芝, 等. 葡萄糖溶液光声信号时域与频域特性对比[J]. 光学精密工程, 2020,28(11):2421-2428.

Qian WANG, Peng-fei LÜ, Qiao-zhi HE, et al. Characteristics comparison of photoacoustic signal of glucose solution in time domain and frequency domain[J]. Optics and precision engineering, 2020, 28(11): 2421-2428.
王倩, 吕鹏飞, 何巧芝, 等. 葡萄糖溶液光声信号时域与频域特性对比[J]. 光学精密工程, 2020,28(11):2421-2428. DOI： 10.37188/OPE.20202811.2421.

Qian WANG, Peng-fei LÜ, Qiao-zhi HE, et al. Characteristics comparison of photoacoustic signal of glucose solution in time domain and frequency domain[J]. Optics and precision engineering, 2020, 28(11): 2421-2428. DOI： 10.37188/OPE.20202811.2421.

摘要

为了克服时域信号易受环境干扰影响的缺陷，提高液体浓度光声测量的稳定性，在已有的光声信号时域峰峰值特性研究的基础上，对光声信号的频域特性展开研究。分别讨论了葡萄糖溶液光声信号的功率谱特性和最大熵谱特性，并分别采用峰值检测、对数拟合等方法对光声信号的频谱特性进行分析。对比了葡萄糖光声信号时域峰峰值与功率谱、最大熵谱的非线性误差和重复性误差。实验结果表明：对最大熵谱曲线进行对数拟合之后采用截距表征光声信号的方法，其非线性误差和重复性误差相比于传统的时域峰峰值检测方法分别减小了28%和71%。由此可以得出：频域分析方法可以显著减小葡萄糖浓度检测的非线性误差和重复性误差，提高无创血糖浓度检测的精度与稳定性。

Abstract

To overcome the shortcomings of the time-domain signal

which is easily affected by environmental interference

and improve the stability of photoacoustic measurements of the liquid concentrations

this study investigated the frequency-domain characteristics of a photoacoustic signal based on the time-domain peak-to-peak characteristics of the photoacoustic signal. The power spectrum characteristics and maximum entropy spectrum characteristics of the photoacoustic signal of glucose solution were evaluated. Different methods

such as peak detection and logarithmic fitting

were used to analyze the spectral characteristics of the photoacoustic signal. The nonlinear error and repeatability error of the time-domain peak detection

power spectrum

and maximum entropy spectrum methods were compared. The experimental results show that by using the intercept to characterize the photoacoustic signal after the logarithmic fitting of the maximum entropy spectrum curve

the nonlinear error and repeatability error can be reduced by 28% and 71%

respectively

compared with the traditional time-domain peak-to-peak detection method. The frequency-domain method can be used to reduce the nonlinear and repeatability errors of glucose concentration detection significantly. Furthermore

the frequency-domain method could improve the accuracy and stability of noninvasive blood glucose concentration detection.

关键词

Keywords

references

N H CHO , J E SHAW , S KARURANGA , 等 . IDF diabetes atlas: global estimates of diabetes prevalence for 2017 and projections for 2045 . Diabetes Research & Clinical Practice , 2018 . 271 .

李晓莉 , 李成伟 . 改进的自适应噪声总体集合经验模态分解在光谱信号去噪中的应用 . 光学精密工程 , 2016 . 24 ( 7 ): 1754 - 1762 . http://ope.lightpublishing.cn/thesisDetails?columnId=1445744&Fpath=&index=-1&l=zh http://ope.lightpublishing.cn/thesisDetails?columnId=1445744&Fpath=&index=-1&l=zh .

X L LI , CH W LI . Application of improved complete ensemble empirical mode decomposition with adaptive noise in spectral signal denoising . Opt. Precision Eng. , 2016 . 24 ( 7 ): 1754 - 1762 . http://ope.lightpublishing.cn/thesisDetails?columnId=1445744&Fpath=&index=-1&l=zh http://ope.lightpublishing.cn/thesisDetails?columnId=1445744&Fpath=&index=-1&l=zh .

徐可欣 , 陈小龙 , 栗大超 , 等 . 基于微流控和酶比色的微创血糖连续检测仪 . 光学精密工程 , 2018 . 26 ( 11 ): 6 - 13 . http://ope.lightpublishing.cn/thesisDetails?columnId=1416341&Fpath=&index=-1&l=zh http://ope.lightpublishing.cn/thesisDetails?columnId=1416341&Fpath=&index=-1&l=zh .

K X XU , X L CHEN , D CH LI , 等 . Minimally invasive continuous blood glucose monitor based on microfluidic and enzyme colorimetric technologies . Opt. Precision Eng. , 2018 . 26 ( 11 ): 6 - 13 . http://ope.lightpublishing.cn/thesisDetails?columnId=1416341&Fpath=&index=-1&l=zh http://ope.lightpublishing.cn/thesisDetails?columnId=1416341&Fpath=&index=-1&l=zh .

S W ZHAO , W TAO , Q Z He , 等 . A new approach to non-invasive blood glucose measurement based on 2-dimension photoacoustic spectrum . Proceeding of IMCCC , 2017 . 8298673 .

吕鹏飞 , 陆志谦 , 何巧芝 , 等 . 基于光声谱法的无创血糖在体检测 . 光学精密工程 , 2019 . 27 ( 6 ): 1301 - 1308 . http://ope.lightpublishing.cn/thesisDetails?columnId=1423359&Fpath=&index=-1&l=zh http://ope.lightpublishing.cn/thesisDetails?columnId=1423359&Fpath=&index=-1&l=zh .

P F LV , ZH Q LU , Q ZH HE , 等 . Non-invasive blood glucose in vivo detection based on photoacoustic spectroscopy . Opt. Precision Eng. , 2019 . 27 ( 6 ): 1301 - 1308 . http://ope.lightpublishing.cn/thesisDetails?columnId=1423359&Fpath=&index=-1&l=zh http://ope.lightpublishing.cn/thesisDetails?columnId=1423359&Fpath=&index=-1&l=zh .

C K N PATEL , A C TAM . Pulsed optoacoustic spectroscopy of condensed matter . Reviews of Modern Physics , 1981 . 53 ( 3 ): 517 - 550 . DOI: 10.1103/RevModPhys.53.517 http://doi.org/10.1103/RevModPhys.53.517 .

M K DASA , C MARKOS , J JANTING , 等 . Multispectral photoacoustic sensing for accurate glucose monitoring using a supercontinuum laser . JOSA B , 2019 . 36 ( 2 ): A61 - A65 . DOI: 10.1364/JOSAB.36.000A61 http://doi.org/10.1364/JOSAB.36.000A61 .

W TAO , Z Q LU , Q Z HE , 等 . Research on the temperature characteristics of the photoacoustic sensor of glucose solution . Sensors , 2018 . 18 ( 12 ): 4323 DOI: 10.3390/s18124323 http://doi.org/10.3390/s18124323 .

S W ZHAO , W TAO , Q Z HE , 等 . A non-invasive photoacoustic and ultrasonic method for the measurement of glucose solution concentration . AIP Advances , 2017 . 7 ( 3 ): 035313 DOI: 10.1063/1.4979110 http://doi.org/10.1063/1.4979110 .

Q ZHOU , S W ZHAO , J S WEI . Parameter estimation of photoacoustic signal for glucose solutions using laplace wavelet correlation filtering and least square estimation . Applied Mechanics and Materials , 2014 . 475 225 - 235 .

胡广书 . 数字信号处理 , : 北京清华大学出版社 , 2013 .

G SH HU . Digital Signal Processing , : Beijing Tsinghua University Press , 2013 .

刘晞远 , 胡昊颖 , 吴珊 , 等 . AR模型的谱分辨率及小信噪比下的性能分析 . 舰船电子工程 , 2018 . 38 ( 7 ): 131 - 136 .

X Y LIU , H Y HU , SH WU , 等 . Performance analysis on spectrum resolution ratio and small noise-signal ratio of AR model-based power spectrum estimation . Ship Electronic Engineering , 2018 . 38 ( 7 ): 131 - 136 .

徐海翔 , 崔正湃 , 吴林林 , 等 . 基于最大熵谱估计的风电功率周期特性的研究征提取 . 太阳能学报 , 2018 . 39 ( 9 ): 2425 - 2431 .

H X XU , ZH P CUI , L L WU , 等 . Study on periodicity of wind power based on maximum entropy spectrum estimation . Acta Energiae Solaris Sinica , 2018 . 39 ( 9 ): 2425 - 2431 .

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