数字微流控芯片上液滴驱动

王洪; 郑杰; 闫延鹏; 王淞; 李浩正; 崔建国

doi:10.37188/OPE.20202811.2488

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数字微流控芯片上液滴驱动

微纳技术与精密机械 | 更新时间：2020-12-09

- 数字微流控芯片上液滴驱动
- Drop driving on digital microfluidic chip
- 光学精密工程 2020年28卷第11期页码：2488-2496
- 作者机构：
  
  重庆理工大学药学与生物工程学院, 重庆 400054
- 作者简介：
  
  [ "王洪(1993-), 男, 重庆奉节人, 硕士, 2017年于重庆理工大学获得学士学位, 主要从事生物医学微系统、小型医学仪器方面的研究。E-mail:whongssrui@163.com" ]
  崔建国(1974-), 男, 辽宁锦州人, 副教授, 博士, 硕士生导师, 1998年于辽宁石油化工大学获得学士学位, 2004年、2008年于重庆大学分别获得硕士、博士学位, 主要从事生物医学系统及智能医疗仪器方面的研究。E-mail:cjg998@hotmail.com CUI Jian-guo, E-mail:cjg998@hotmail.com
- 基金信息：
  
  国家科技支撑计划资助项目(2015BAI01B14);重庆市高等教育教学改革研究一般项目(173114);重庆理工大学研究生教育优质课程项目资助(yyk2017106);重庆市技术创新与应用示范（社会民生类）一般项目(cstc2018jscx-msyb0290)
- DOI：10.37188/OPE.20202811.2488
  中图分类号： TP273;TN492
- 收稿日期：2020-06-01，
  
  修回日期：2020-06-11，
  
  录用日期：2020-6-11，
  
  纸质出版日期：2020-11-25
- 稿件说明：
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王洪, 郑杰, 闫延鹏, 等. 数字微流控芯片上液滴驱动[J]. 光学精密工程, 2020,28(11):2488-2496.

Hong WANG, Jie ZHENG, Yan-peng YAN, et al. Drop driving on digital microfluidic chip[J]. Optics and precision engineering, 2020, 28(11): 2488-2496.
王洪, 郑杰, 闫延鹏, 等. 数字微流控芯片上液滴驱动[J]. 光学精密工程, 2020,28(11):2488-2496. DOI： 10.37188/OPE.20202811.2488.

Hong WANG, Jie ZHENG, Yan-peng YAN, et al. Drop driving on digital microfluidic chip[J]. Optics and precision engineering, 2020, 28(11): 2488-2496. DOI： 10.37188/OPE.20202811.2488.

摘要

为提高数字微流控芯片上液滴驱动能力及效率，开展了数字微流控系统的设计及平台搭建研究，该系统包括上位机控制软件、下位机硬件系统和DMF芯片三部分。提出一种曲边四边形组合电极，该电极图形边缘能与液滴保持更大的重合度，可提供更大的初始驱动力。测试了芯片上空气浴和油浴中液滴的驱动控制，测得在空气浴中碳酸丙烯脂液滴的平均速度为25 μm/s，在油浴中碳酸丙烯脂液滴的平均速度为260 μm/s。实验结果表明，所设计的曲边四边形电极可有效增强液滴的驱动控制能力。

Abstract

To improve the driving capability and efficiency of droplets on a digital microfluidic (DMF) chip

a DMF system was designed and platform building research was conducted. The system includes three parts: upper computer control software

a lower computer hardware system

and a DMF chip. A curved quadrilateral combined electrode is proposed. The edge of the electrode pattern can maintain a greater degree of coincidence with the droplet and can provide a greater initial driving force. Drive control of the droplets in air and oil baths on the chip was tested

and the average velocities of propylene carbonate droplets were measured to be 25 and 260 μm/s in air and oil baths

respectively. The experimental results demonstrate that the curved quadrilateral electrode designed in the study can effectively enhance drive control of the droplet.

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references

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