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天津大学 教育部光电信息与技术重点实验室,天津 300072
收稿日期:2009-10-13,
修回日期:2009-12-10,
网络出版日期:2010-08-20,
纸质出版日期:2010-08-20
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陈晓冬, 汪 毅, 李海峰, 李 乔, 郁道银. 单探测器偏振相干层析信号的傅里叶变换分析[J]. 光学精密工程, 2010,18(8): 1746-1753
CHEN Xiao-dong, WANG Yi, LI Hai-feng, LI Qiao, YU Dao-yin. Fast Fourier transform analysis of single-detector polarization-sensitive optical coherence tomographic signals[J]. 光学精密工程, 2010,18(8): 1746-1753
陈晓冬, 汪 毅, 李海峰, 李 乔, 郁道银. 单探测器偏振相干层析信号的傅里叶变换分析[J]. 光学精密工程, 2010,18(8): 1746-1753 DOI: 10.3788/OPE.20101808.1746.
CHEN Xiao-dong, WANG Yi, LI Hai-feng, LI Qiao, YU Dao-yin. Fast Fourier transform analysis of single-detector polarization-sensitive optical coherence tomographic signals[J]. 光学精密工程, 2010,18(8): 1746-1753 DOI: 10.3788/OPE.20101808.1746.
研究了生物组织的双折射率、质地密度及层次结构等不同特性对单探测器偏振相干层析(PS-OCT)信号傅里叶频谱的影响。探讨了单探测器PS-OCT的成像理论
建立了多层组织模型。以该模型为样品模拟了它的单探测器偏振OCT信号
并分析了不同模型参数对信号傅立叶频谱的影响。以牛软骨、新鲜及干牛腱为样品
利用单探测器PS-OCT系统对它们进行A型扫描
并对获得的数据进行傅里叶变换。获得的傅里叶频谱显示
随着样品双折射率、背散射率、结构层次等特性的改变
频谱中的谱峰形状及所对应的频率也发生变化
结果证实了单探测器PS-OCT系统检测多种生物组织特性的能力。
This paper focused on the relationship of the biological tissue character and the Fast Fourier Transform(FFT) of Polarization-sensitive Optical Coherence Tomography(PS-OCT) signals
and researched the influence of the birefringence
texture and the structure of tissues on the FFT of PS-OCT signals. After describing the single-detector PS-OCT imaging theory in detail
it set up a three-layer tissue model. On the basis of the model
it simulated its single detector PS-OCT signals and analyzed the influence of different model parameters on the FFT of signals. By taking the bovine tendons and cartilages as samples
a A-scan experiment was carried out with the single detector PS-OCT system.Obtained FFT shows that the spectral shapes and relative frequencies change with the different tissue characters
such as birefringence
back scattering indexes and structures. The researches approve the ability of single-detector PS-OCT in detecting biological tissue characters.
HITZENBERGER C K. Imaging of polarization properties of the human cornea with phase resolved polarization sensitive optical coherence tomography[J]. SPIE, 2003,4951:21-26.
BOER J F, MILNER T E. Review of polarization sensitive optical coherence tomography and Stokes vector determination[J]. Journal of Biomedical Optics, 2002,7(3):359-371.
GOTZENGER E, PIRCHER M, HITZENBERGER C K. High speed spectral domain polarization sensitive optical coherence tomography of the human retina[J]. Optics Express, 2005,13(25):10217-10229.
MAKITA S, YASUNO Y, ENDO T, et al.. Polarization contrast imaging of biological tissues by polarization-sensitive Fourier-domain optical coherence tomography[J]. Applied Optics, 2006,45(6):1142-1147.
YANG Y, WU L, FENG Y, et al.. Observations of birefringence in tissues from optic-fibre-based optical coherence tomography[J]. Measurement Science and Technology, 2003,14:41-46.
CHEN Y, OTIS L, PIAO D Q, et al.. Characterization of dentin, enamel and carious lesions by a polarization-sensitive optical coherence tomography system[J]. Applied Optics, 2005,44:2041-2047.
CENSEL B, MUJAT M, CHEN T C, et al.. Polarization-sensitive spectral-domain optical coherence tomography using a single line scan camera[J]. Optics Express, 2007,15(5):2421-2431.
LIU B, HARMAN M, BREZINSKI M E. Variables affecting polarization-sensitive optical coherence tomography imaging examined through the modeling of birefringent phantoms [J]. J. Opt. Soc. Am. A, 2005,22(2):262-271.
LIU B, HARMAN M, GIATTINA S, et al.. Characterizing of tissue microstructure with single-detector polarization-sensitive optical coherence tomography[J]. Applied Optics, 2006,45(18):4464-4479.
何卫红, 何永红, 李鹏,等. 眼底OCT成像系统的研制[J]. 光学精密工程, 2008,16(3): 438-443.
HE W H, HE Y H, LI P, et al.. Development of imaging system for optical coherence tomography in ophthalmology[J]. Opt. Precision Eng., 2008,16(3):438-443.(in Chinese)
曾楠, 何永红, 马辉. 用于玉石结构分析的光学相干层析技术[J]. 光学精密工程, 2008,16(7):1335-1342.
ZENG N, HE Y H, MA H. Imageing and analyzing subsurface morphologies of jade objects with optical coherence tomography[J]. Opt. Precision Eng., 2008,16(7):1335-1342.(in Chinese)
柯丽, 杜强, 苏哲. 应用多级维纳滤波的OCT图像除噪方法[J]. 光学精密工程, 2008, 16(4):740-745.
KE L, DU Q, SU Z. OCT image denoising method based on multi-scale Wiener filtering[J]. Opt. Precision Eng., 2008,16(4):740-745.(in Chinese)
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