谱域OCT成像系统在口腔组织检测中的应用

彭诚; 张芹芹; 吴晓静; 朱思伟; 高志; 袁小聪

doi:10.3788/OPE.20111908.1931

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谱域OCT成像系统在口腔组织检测中的应用

信息科学 | 更新时间：2020-08-12

- 谱域OCT成像系统在口腔组织检测中的应用
- Application of spectral domain optical coherence tomography to oral cavity tissue test
- 光学精密工程 2011年19卷第8期页码：1931-1936
- 作者机构：
  
  1. 天津医科大学第二医院口腔科天津,300211
  2. 南开大学现代光学研究所光电信息技术科学教育部重点实验室天津,300071
  3. 南开大学人民医院分子医学与纳米光学实验室天津,300121
  4. Department of Bioengineering, Clemson University, Clemson, South Carolina,USA,29634
- 作者简介：
- 基金信息：
  
  天津市高等学校科技发展计划资助项目(No.20060123)()
- DOI：10.3788/OPE.20111908.1931
  中图分类号： R781.7;R814.42
- 收稿日期：2011-03-03，
  
  修回日期：2011-03-18，
  
  网络出版日期：2011-08-25，
  
  纸质出版日期：2011-08-25
- 稿件说明：
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彭诚, 张芹芹, 吴晓静, 朱思伟, 高志, 袁小聪. 谱域OCT成像系统在口腔组织检测中的应用[J]. 光学精密工程, 2011,19(8): 1931-1936

PENG Cheng, ZHANG Qin-qin, WU Xiao-jing, ZHU Si-wei, GAO Zhi, YUAN Xiao-cong. Application of spectral domain optical coherence tomography to oral cavity tissue test[J]. Editorial Office of Optics and Precision Engineering, 2011,19(8): 1931-1936
彭诚, 张芹芹, 吴晓静, 朱思伟, 高志, 袁小聪. 谱域OCT成像系统在口腔组织检测中的应用[J]. 光学精密工程, 2011,19(8): 1931-1936 DOI： 10.3788/OPE.20111908.1931.

PENG Cheng, ZHANG Qin-qin, WU Xiao-jing, ZHU Si-wei, GAO Zhi, YUAN Xiao-cong. Application of spectral domain optical coherence tomography to oral cavity tissue test[J]. Editorial Office of Optics and Precision Engineering, 2011,19(8): 1931-1936 DOI： 10.3788/OPE.20111908.1931.

摘要

基于谱域光学相干层析术理论设计并搭建了一套便于集成化的光纤式谱域OCT系统

其纵向分辨率为7.3 m

横向分辨率为9.5 m

在空气中的成像深度为3.14 mm。该系统通过干涉光谱来获得样品的深度信息

实现数据的高速采集。利用该系统对口腔内唾液腺导管内壁的组织形态进行了研究

并将得到的OCT图像与相对应的病理切片图片进行了比较。实验结果表明

采用研制的系统可以获得腮腺导管内壁组织的层析结构。该项研究对临床医学上的口腔唾液腺疾病的无创检查和早期诊断具有指导意义。

Abstract

On the basis of the concept of Spectral Domain Optical Coherence Tomography (SDOCT)

a fiber type SDOCT system which is easy to integration was developed. The system shows its longitudinal resolution in 7.3 m

lateral resolution in 9.5 m and offers the imaging depth to be 3.14 mm in air. The system obtains the sample deeply by a interferometer

which achieves the dada collection fast. The organizational features of salivary glands were researched by the above system

and the OCT images for the parotid glands were compared with that of the pathological section. Results show that the system proposed can provide a direction for the early diagnosis and the non-harmful examination of the oral cavity tissue.

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references

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