微纳流体光波导技术及其在生物传感器中的应用

黎永前; 苏磊; 满力; 寿宸; 叶芳; 徐征

doi:10.3788/OPE.20132104.0987

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微纳流体光波导技术及其在生物传感器中的应用

微纳技术与精密机械 | 更新时间：2020-08-12

- 微纳流体光波导技术及其在生物传感器中的应用
- Optofluidic waveguides and their applications to biological sensors
- 光学精密工程 2013年21卷第4期页码：987-999
- 作者机构：
  
  1. 西北工业大学空天微纳系统教育部重点实验室
  2. 大连理工大学辽宁省微纳米技术及系统重点实验室
- 作者简介：
- 基金信息：
  
  国家自然科学基金(41301448)
- DOI：10.3788/OPE.20132104.0987
  中图分类号： TN252;TP212.3
- 收稿日期：2012-11-02，
  
  修回日期：2012-12-25，
  
  网络出版日期：2013-04-20，
  
  纸质出版日期：2013-04-15
- 稿件说明：
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黎永前苏磊满力寿宸叶芳徐征. 微纳流体光波导技术及其在生物传感器中的应用[J]. 光学精密工程, 2013,21(4): 987-999

LI Yong-Qian SU Lei MAN Li SHOU Chen YE Fang XU Zheng. Optofluidic waveguides and their applications to biological sensors[J]. Editorial Office of Optics and Precision Engineering, 2013,21(4): 987-999
黎永前苏磊满力寿宸叶芳徐征. 微纳流体光波导技术及其在生物传感器中的应用[J]. 光学精密工程, 2013,21(4): 987-999 DOI： 10.3788/OPE.20132104.0987.

LI Yong-Qian SU Lei MAN Li SHOU Chen YE Fang XU Zheng. Optofluidic waveguides and their applications to biological sensors[J]. Editorial Office of Optics and Precision Engineering, 2013,21(4): 987-999 DOI： 10.3788/OPE.20132104.0987.

摘要

微纳流体光波导融合了微观流体与微光学特征，能够在相同物理空间实现流体介质和微光学信息功能及结构的集成，是生物化学分析及生物传感器的关键器件。本文综述了微纳流体光波导研究现状及其在生物传感器和生物化学分析中的应用实例。论述了实现微纳流体光波导的全反射机理、多层干涉效应，抗谐振反射机理，以及基于上述机理实现的各种流体波导形式。重点分析了基于微纳流体层流效应的全流体波导，基于多层干涉效应的Bragg光波导、空心光子晶体波导、狭缝光流体波导、抗谐振反射光波导等多种波导的特点。指出狭缝光流体波导和抗谐振反射光波导具有更好的设计灵活性，且检测灵敏度高、可靠性好、易于集成制造，可望在生物传感器及微纳流体光学系统中得到更广泛的应用。

Abstract

Optofluidic waveguides can integrate the functions and structures of fluid media and micro-optical information in the same physical space because of the fusion of the microfluidic/nanofluidics and the micro-optics. They have been the key devices for biochemical analysis and biosensors. This paper overviews the research status of the optofluidic waveguides and their applications to biochemical analysis and biosensors. It describes the basic principles to implement different fluid waveguides

such as total reflection principles

multi-layer interference effect and antiresonant reflecting mechanism

and gives a lots of waveguide forms according to the principles mentioned above. It focuses on the analysis of the characteristics of total fluid waveguides based on micro/nano fluidic layers

Bragg waveguides based on interference effect

hollow core photonic crystal waveguides

slit fluid waveguides and antiresonant reflecting waveguides. Finally

it points out that the latter two waveguides can be designed in flexibility and is characterized by higher sensibility

good reliability and easy to be fabricated

so that they are expected to widely used in biosensors and microfluidic/nanofluidic systems.

关键词

Keywords

references

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