可降解心脏支架的飞秒激光精密加工

程萍; 位迪; 吴本科; 高峰; 陈向东

doi:10.3788/OPE.20142201.0063

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可降解心脏支架的飞秒激光精密加工

现代应用光学 | 更新时间：2020-08-13

- 可降解心脏支架的飞秒激光精密加工
- Femtosecond laser precision machining of biodegradable heart stent
- 光学精密工程 2014年22卷第1期页码：63-68
- 作者机构：
  
  合肥工业大学电子科学与应用物理学院,安徽合肥,230009
- 作者简介：
- 基金信息：
  
  国家自然科学基金资助项目(No.61154004)()
- DOI：10.3788/OPE.20142201.0063
  中图分类号： TG665;R318.11
- 收稿日期：2013-09-13，
  
  纸质出版日期：2014-01-15
- 稿件说明：
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程萍, 位迪, 吴本科等. 可降解心脏支架的飞秒激光精密加工[J]. 光学精密工程, 2014,22(1): 63-68

CHENG Ping, WEI Di, WU Ben-ke etc. Femtosecond laser precision machining of biodegradable heart stent[J]. Editorial Office of Optics and Precision Engineering, 2014,22(1): 63-68
程萍, 位迪, 吴本科等. 可降解心脏支架的飞秒激光精密加工[J]. 光学精密工程, 2014,22(1): 63-68 DOI： 10.3788/OPE.20142201.0063.

CHENG Ping, WEI Di, WU Ben-ke etc. Femtosecond laser precision machining of biodegradable heart stent[J]. Editorial Office of Optics and Precision Engineering, 2014,22(1): 63-68 DOI： 10.3788/OPE.20142201.0063.

摘要

以激光精密加工金属血管心脏支架生产工艺为基础

探索了可降解心脏支架的飞秒激光精密加工方式。利用飞秒激光的超短脉冲和超高峰值功率的特性

实现了以聚乳酸(PLA) 为材料的可降解心脏支架的激光精密加工。设计了椅形衬套

稳定了激光焦斑位置

分析得出了最佳衬套离焦距用于配合飞秒激光精密加工。通过调试工艺参量

解决了由于材料本身特性引起的切缝边缘易炭化和加工过程中由于离焦量和焦斑位置准确度不稳定导致不能精密加工的问题

实现了对非金属可降解心脏支架的无热精密加工。说明了飞秒激光配合椅形衬套加工非金属血管支架的可行性

确定了最佳加工参量

加工出了无热损伤切边光滑筋宽一致性为±6 μm的可降解心脏支架样品。

Abstract

On the basis of the traditional laser precision machining technologies for metal heart stents

a femtoseconds(fs) laser precision machining technology for a degradable heart stent was explored. By using the ultra-short pulse and ultra high peak power of the fs laser

the laser precision machining was implemented for the degradable heart stent made from the polylactic acid (PLA). A chair shaped bushing was designed to stabilize the laser focal spot position and the best bushing from focal precision machining was obtained to match with fs laser machining. By adjusting technological parameters

the shortcomings of the cutting edge carbonization caused by the characteristics of the material itself and the lower machining precision due to the unstable defocusing and focal spot position were overcome

and a nonmetal degradable heart stent method in a no heat precision machining was proposed. Finally

the feasibility of fs laser with chair-shaped bushing to machine a nonmetallic stent was described

the best machining parameters were determined

and a biodegradable stent sample without heat injury trimming and with a smooth band width consistency of ± 6 μ m was machined successfully.

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Keywords

references

黄楚波, 敖宁建. 可降解冠状动脉血管支架的设计与激光加工 [J].应用激光, 2007, 27(3):224-226.

HUANG CH B, AO N J. Novel biodegradable coronary stents: design and laser microprocessing [J] . Applied laser, 2007, 27(3):224-226.(in Chinese)

黄远, 田筝, 刘文西, 等. 加工工艺对医用心血管支架生物相容性的影响[J]. 天津大学学报, 2003, 36(3):374-379.

HUANG Y, TIAN ZH, LIU W X, et al.. Influence of process techniques on biocomp atibilityof coronary artery stent [J]. Journal of Tianjin University, 2004, 34(5):595-622. (in Chinese)

黄超, 刘秋明, 叶宽, 等. 介入治疗用非血管可降解支架的研究进展[J]. 高分子通报, 2012, 7: 15-21.

HUANG CH, LIU Q M, YE K, et al.. Research progress of biodegradable stent in terventional treatment can be used in non vascular [J]. Polymer Bulletin., 2012, 7: 15-21.(in Chinese)

魏志勇, 刘炼, 齐民.生物可降解血管内支架研究进展[J]. 生物医学工程学杂志, 2008, 25(5):1226-1230.

WEI ZH Y, LIU L, QI M. Progress in researches of biodegradable intravascular stents [J]. Journal of Biomedical Engineering, 2008, 25 (5): 1226-1230.(in Chinese)

史文红, 赵成如, 金刚. 静电纺丝技术在生物医用材料领域中的应用[J]. 材料与制造, 2006, 05: 17-22.

SHI W H, ZHAO CH R, JIN G. The application of electrospinning technique in the biomedical materials field [J]. Material and Manufacture, 2006, 5: 17-22.(in Chinese)

徐斌, 伍晓宇, 罗烽, 等. 0Cr18Ni9不锈钢箔的飞秒激光烧蚀[J]. 光学精密工程, 2012, 20 (1): 45-51.

XU B, WU X Y, LUO F, et al.. Ablation of 0Cr18Ni9 stainless steel films by femtosecond laser [J]. Opt. Precision Eng., 2012, 20 (1): 45-51.(in Chinese)

徐斌, 伍晓宇, 凌世全, 等.飞秒激光切割与微细电阻滑焊组合制备三维金属微结构[J]. 光学精密工程, 2012, 20 (8): 1811-1823.

XU B, WU X Y, LING SH Q, et al.. Fabrication of 3D metal micro-structure based on fs laser cutting and micro electric resistance slip welding [J]. Opt. Precision Eng., 2012, 20 (8): 1811-1823.(in Chinese)

TRTICA M S, GAKOVIC B M, RADAK B B, et al.. Material surface modification by ns, ps and fs laser pulse [J]. Opt. Precision Eng., 2011, 19 (2): 221-227.

CHENGDE L, SUWAS N, FRANKLIN W.An optimal process of femtosecond laser cuttingof NiTi shape memory alloy for fabrication of miniature devices [J]. Optics and Lasers in Engineering, 2006, 44(16): 1078-1087.

FRIEDRICH D, MIKHAIL L.Variable disk laser for optimized micro machining [J]. Physics Procedia, 2010, 5(10):101-108.

蒙红云, 廖健宏, 官邦贵, 等. 心血管支架的光纤激光切割工艺[J]. 中国激光, 2007, 34(5):733-736.

MENG H Y, LIAO J H, GUAN B G, et al.. Fiber laser cutting technology on coronary artery stent[J]. Chinese Journal of Lasers, 2007, 34(5):733-736. (in Chinese)

顾兴中, 倪中华. 微孔结构血管支架的激光切割工艺[J]. 华中科技大学学报, 2007, 35(1):143-146.

GU X ZH, NI ZH H.The fabrication of micro-hole stent by laser cutting[J]. J. Huazhong Univ. of Sci. & Tech. (Nature Science Edition), 2007, 35(1):143-146.(in Chinese)

杨建军.飞秒激光超精细‘冷’加工技术及其应用[J]. 激光与光电子学进展, 2004, 41(3):42-52.

YANG J J. Femtosecond laser“Cold” micro-machining and its advanced applicationgs[J]. Laser & Optoelectronics Progress, 2004, 41(3):42-52. (in Chinese)

MUHAMMAD N, WHITEHEAD D, BOOR A. Comparison of dry and wet fibre laser profile cutting of thin 316L stainless steel tubes for medical device applications [J]. Journal of Materials Processing Technology, 2010, 210: 2261-2267.

DHKAM, SHAH L, MAZUMDER J. Femtosecond laser machining of multi-depth microchannel networks onto silicon [J]. J. Micromech. Microeng., 2011, 21(4) : 5027-5034.

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