医用显微成像光谱仪的光谱定标技术

魏巍; 崔继承; 唐玉国; 孙慈; 潘明忠

doi:10.3788/OPE.20162405.1015

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医用显微成像光谱仪的光谱定标技术

现代应用光学 | 更新时间：2020-08-13

- 医用显微成像光谱仪的光谱定标技术
- Spectral calibration of medical microscopic imaging spectrometer
- 光学精密工程 2016年24卷第5期页码：1015-1020
- 作者机构：
  
  1. 中国科学院长春光学精密机械与物理研究所,吉林长春,中国,130033
  2. 中国科学院大学北京,中国,100049
  3. 长春工业大学,吉林长春,130012
- 作者简介：
- 基金信息：
  
  国家自然科学基金资助项目(No.61108032)();吉林省科技发展计划资助项目(No.20126012)()
- DOI：10.3788/OPE.20162405.1015
  中图分类号： TH773;TH744.1
- 收稿日期：2016-01-08，
  
  修回日期：2016-02-19，
  
  网络出版日期：2016-03-30，
  
  纸质出版日期：2016-05-25
- 稿件说明：
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魏巍, 崔继承, 唐玉国等. 医用显微成像光谱仪的光谱定标技术[J]. 光学精密工程, 2016,24(5): 1015-1020

WEI Wei, CUI Ji-cheng, TANG Yu-guo etc. Spectral calibration of medical microscopic imaging spectrometer[J]. Editorial Office of Optics and Precision Engineering, 2016,24(5): 1015-1020
魏巍, 崔继承, 唐玉国等. 医用显微成像光谱仪的光谱定标技术[J]. 光学精密工程, 2016,24(5): 1015-1020 DOI： 10.3788/OPE.20162405.1015.

WEI Wei, CUI Ji-cheng, TANG Yu-guo etc. Spectral calibration of medical microscopic imaging spectrometer[J]. Editorial Office of Optics and Precision Engineering, 2016,24(5): 1015-1020 DOI： 10.3788/OPE.20162405.1015.

摘要

为了能对自主研制的脑肿瘤手术医用显微成像光谱仪进行光谱定标

设计了由单色仪、钨灯光源、棱镜-光栅-棱镜成像光谱仪及手术显微平台组成的光谱定标系统。采用单色仪波长扫描法

自主开发了相应的光谱定标系统软件

获得了显微成像光谱仪全谱段的光谱数据

完成了数据处理和分析等工作。通过调整光路、单色仪定标、成像光谱仪定标3个步骤实现了系统的光谱定标。定标结果表明:显微成像光谱仪的光谱区大于400~900 nm;定标精度高于0.1 nm

光谱分辨率高于3 nm

各项特征指标均高于设计指标。测试验证实验表明

所建立的光谱定标系统定标精准

结构简单、紧凑

操作简单

符合显微成像光谱仪的实际临床应用要求。

Abstract

To accomplish the spectral calibration of a medical microscopic imaging spectrometer developed by ourselves for brain tumor operation

a spectral calibration system was designed. The system is composed of a monochromator

a tungsten-light source

a surgical microscope platform and a prism-grating-prism(PGP) imaging spectrometer. A software for spectral calibration was developed based on monochromator wavelength scanning method

the spectral data of the medical microscopic imaging spectrometer in full bands were obtained and the data processing and data analysis were performed. The spectral calibration was implemented by adjusting path

monochromator calibration and imager calibration. Experimental results show that the accuracy of the spectral calibration is better than 0.1 nm

the spectral ranges of the imaging spectrometer are greater than 400-900 nm and its spectral resolution is better than 3 nm. The test validation shows that the spectral calibration system is accurate

simple

compact

and easy to operate and meets the actual clinical requirements of microscopic imaging spectrometers.

关键词

Keywords

references

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